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  • Contrave is looking very promising for those seeking dieting pill that works. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs potential risk of a possible surge in blood pressure.

    Using two separate drugs to lose weight naturally can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the those who go through it you ought to err to the side of caution and let the FDA do its job and demand some study be done so the public is aware of the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on his or her medications.

    Researchers found out that participants using this drug for the year, dropped a few pounds within four weeks and have kept the weight off through the 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs which are made up of many active ingredient, which may make them more potent and safer.

    Combo-pilling is the newest fad or also the newest to come under scrutiny and thus it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular is the fact that by right now there are no long term prescription diet pills that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug could also raise blood pressure level and heart rate, and mustn't be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high blood pressure level, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    "This could be the first drug I'm conscious of that targets both appetite and reward centres inside the brain," he said.