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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight-loss in addition to a reduced-calorie diet and physical exercise.

    Using two separate drugs to lose weight naturally can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err on the side of caution and let the FDA do its job and demand some study be done in order that the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on their medications.

    Researchers discovered that participants investing in this drug for a year, lost excess weight within a month and have kept the weight off through the 56 weeks with the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more effective and safer.

    Combo-pilling may be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that at the time of right now there are not any long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and really should not be taken in those with seizure disorders. The drug can also raise blood pressure and heartrate, and must not be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high blood pressure, and also by you are not heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients on the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

    Approving a drug with this many potentially lethal negative effects is inconsistent while using mission statement of the FDA. The power in the drug manufacturing lobby is blatantly evident inside approval of many drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety inside US.