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  • The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

    Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err on the side of caution and allow the FDA do its job and demand some investigation be done so the public recognizes the side effects and hazards of the medications before we bring them. Keep in mind that drug companies have been in business to generate money and that they would say almost anything to keep people on the medications.

    Researchers found out that participants taking this drug for a year, dropped a few pounds within four weeks and have kept the weight off throughout the 56 weeks from the study. Contrave is a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of multiple active ingredient, which may make them far better and safer.

    Combo-pilling is the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is becoming popular is the fact that as of right now there are no long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be licensed by the FDA.

    Seizures are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug can also raise blood pressure level and heartrate, and must not be used in those with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not used in patients with uncontrolled high blood pressure level, in addition to by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.