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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight-loss in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you should err to the side of caution and permit the FDA do its job and demand some investigation be done so that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say almost anything to keep people on his or her medications.

    Researchers found that participants taking this drug for the year, dropped excess weight within 4 weeks and have kept the weight off through the 56 weeks from the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs that are made up of multiple active ingredient, which might make them far better and safer.

    Combo-pilling is the newest fad or also the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular is the fact that as of right now there aren't long term prescription diet pills that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA.

    Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure and heartrate, and mustn't be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure and heartrate and must 't be used in patients with uncontrolled high blood pressure, in addition to by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    Other people who should avoid using Contrave are patients struggling with bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave really should not be prescribed for ladies who are pregnant or trying to become pregnant.